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in-cites, August 2006
Citing URL: http://www.in-cites.com/institutions/JoslinDiabetesCenter.html

Institutions

             
An interview with:
Joslin Diabetes Center
           

Earlier this year, the Joslin Diabetes Center was named a Rising Star in the field of Biology & Biochemistry. According to Essential Science Indicators, Joslin’s current record in this field includes 177 papers cited a total of 6,092 times to date. Their record also includes 376 papers cited a total of 13,282 times to date in the field of Clinical Medicine. This month, in-cites talks with Dr. George King about Joslin’s citation achievements. Dr. King is the Director of Research and Head of the Section on Vascular Cell Biology at Joslin Diabetes Center, as well as Professor of Medicine at Harvard Medical School.

  How do you account for Joslin Diabetes Center’s significant increase in the number of citations in the field of Biology & Biochemistry in recent years?

The increase in citations is due to multiple factors:

  1. Our investigators are publishing a large number of papers on subjects because they are on the cutting edge of biology and biochemistry. Their findings have stimulated a great deal of excitement for many investigators not only in the areas of diabetes and obesity, but also inJoslin Diabetes Center the general basic sciences—immunology, cell signaling, vascular cell biology, and genetics.
  2. Joslin has recruited several important scientists in the areas of immunology, stem cell biology, and developmental biology. These investigators have published a number of exciting new papers, thereby increasing the visibility of Joslin Diabetes Center.
  3. Diabetes, its complications, and obesity are among the hottest research topics in the field, both in clinical and basic science. Therefore, a large number of investigators have ventured into these areas, which have long been an interest of Joslin scientists. Because the number of papers published in these areas has greatly increased, this could partially explain the increase in citations.

  Does this reflect a deliberate plan to enhance the Center’s research effort in this field, or was this an unexpected or serendipitous development?

Our strategic plans have been formulated over the last five to seven years with extension into multiple fields. Clearly this is part of our strategic plan and therefore is not a serendipitous development.

  Are there specific areas of research within the realm of diabetes on which the center particularly focuses?


“Since 1898, Joslin Diabetes Center has focused its efforts on understanding and finding treatments for people with diabetes.”

Photo by MJMaloney 2005

Joslin Diabetes Center has a narrow mission—to conquer diabetes in all of its forms—but a wide research base. Our main focus is on diabetes, obesity, and associated complications, both in clinical and basic research. However, within those areas we have broad interests, including: immunology, stem cell biology, cell signaling, adipocyte biology, genetics, epidemiology, vascular cell biology, hypertension, diabetic retinopathy, mental health, and many other topics related to diabetes.

  What factors or circumstances led the Center to its work in this field?

Since 1898, Joslin Diabetes Center has focused its efforts on understanding and finding treatments for people with diabetes. Thus we have a longstanding interest in this area. Over the last 20 years we have focused our efforts mainly in basic and clinical research to understand the causes of type 1 diabetes, type 2 diabetes, and vascular complications. Our recent effort has been to translate the basic information into new therapies for the prevention and treatment of type 1 and type 2 diabetes and their frequent complications.

  What is your prediction for the state of our knowledge about this particular field 10 years from now?

The basic science on the causes of type 1 and type 2 diabetes and its complications is rapidly advancing. There is a great deal of interest and many findings in clinical and translational research. Therefore, I believe that over the next 10 years there will be tremendous advances in the understanding of the causes of diabetes. In addition, translational research will produce important information and new therapies for the prevention and treatment of type 1 and type 2 diabetes and its complications.

  What research fields or capabilities do you see as critical for the future of the Center?

In the next few years, the areas of strategic importance will be clinical research with regard to type 1 and type 2 diabetes, stem cell biology, transplantation immunology, prevention of type 1 diabetes, vascular biology, neuroscience, and cardiovascular disease.

  What are the implications of the Center’s work for the future of this particular field or neighboring fields?

The scientific areas being explored in Joslin Diabetes Center’s Research Division have important implications for all sciences. Examples include the understanding of T-cell action, regulation of energy metabolism, and basic signaling of cytokines. Our translational research on imaging of the retina and the pancreas will also be critical models for the study of other diseases.End of interview

George L. King, MD, Director of Research and Head of the Section on Vascular Cell Biology
Joslin Diabetes Center
Boston, MA, USA

Joslin Diabetes Center's most-cited paper with 462 cites to date:
Shepherd PR, Withers DJ, Siddle K, "Phosphoinositide 3-kinase: the key switch mechanism in insulin signalling," Biochem. J. 333:471-90, 1 August 1998.

Source: Essential Science Indicators

   

in-cites, August 2006
Citing URL: http://www.in-cites.com/institutions/JoslinDiabetesCenter.html


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