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"Initial sequencing and analysis of
the human genome," by Eric S.
Lander and 241 others (the International Human Genome Sequencing Consortium), Nature,
409(6822):860-921, 15 February 2001.
[Authors' affiliations: 20 groups worldwide]
From the introduction: "Here we
report the results of a collaboration involving 20 groups from the United
States, the United Kingdom, Japan, France, Germany and China to produce a
draft sequence of the human genome. The draft genome sequence was generated
from a physical map covering more than 96% of the euchromatic part of the
human genome and, together with additional sequence in public databases, it
covers about 94% of the human genome. The sequence was produced over a
relatively short period, with coverage rising from about 10% to more than 90%
over roughly fifteen months. The sequence data have been made available
without restriction and updated daily throughout the project. The task ahead
is to produce a finished sequence, by closing all gaps and resolving all
ambiguities. Already about one billion bases are in final form and the task of
bringing the vast majority of the sequence to this standard is now
straightforward and should proceed rapidly...."
This 2001 report from Nature,
representing the publicly funded effort to sequence the human genome, was
cited approximately 130 times in current journal articles indexed in
the ISI database during September-October 2001. No other paper in biology
published in the last two years attracted as many citations during that two
month period, although a paper in Science, representing the privately
funded effort and published simultaneously with the Nature report, also
collected more than 100 citations during the September-October tally. As of
early December, the Nature paper had logged upwards of 500 citations.
Total citations to date: 495
SOURCE: Hot
Papers Database (Available from the ISI
Research Services Group in a CD-ROM version containing data on
hundreds of highly cited papers published during the last two years.
User interface permits searching by author, organization, journal,
field, and more. Total citations, as well as citations accrued during
successive bimonthly periods, can be assessed and graphed. Database is
combined with subscription to the ISI newsletter Science
Watch®; updated discs containing the
most recent bimonthly data are mailed with each new issue, six times a
year.)
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